Create a bootable disc in Win98 and boot up with it and then remove it?
Most likely the filesystem will be NTFS, which Windows 98 can't read. Ran into that little 'gotcha' myself when trying a Win95 boot disk on a computer using the Win98 FAT32 system...
Anyway, some other things to check for if spyware exhibits itself even in safe mode:
- Many of them embedd themselves as IE plugins, which can get activated as soon as you launch internet explorer... So even in safe mode, as soon as you start IE there's a chance you have 'bonus' programs in memory.
- Some of the particulary nasty ones install themselves as a service or as a fake driver under windows, and mark themselves as essential/critical -- meaning that they will get loaded upon startup even in safe mode.
(I've seen one pretend to be a network adapter driver on my own system years ago. Those can look perfectly legit, until you realize you don't actually have the piece of hardware associated with it installed in your computer)
Fun, eh?